The AIMR Lab Keck School of Medicine

Research

This page highlights key publications, categorized by tags, authors, or topics, providing quick access to the lab’s scientific contributions.

All

2024

Editorial: Advances in artificial intelligence and machine learning applications for the imaging of bone and soft tissue tumors.
Brandon K K Fields, Bino A Varghese, George R Matcuk
Frontiers in radiology  ·  17 Dec 2024  ·  pubmed:39742350
Artificial intelligence and machine learning applications for the imaging of bone and soft tissue tumors.
Paniz Sabeghi, Ketki K Kinkar, Gloria Del Rosario Castaneda, Liesl S Eibschutz, Brandon K K Fields, Bino A Varghese, Dakshesh B Patel, Ali Gholamrezanezhad
Frontiers in radiology  ·  05 Sep 2024  ·  pubmed:39301168
Prediction of future dementia among patients with mild cognitive impairment (MCI) by integrating multimodal clinical data
Andrew Cirincione, Kirsten Lynch, Jamie Bennett, Jeiran Choupan, Bino Varghese, Nasim Sheikh-Bahaei, Gaurav Pandey
Heliyon  ·  01 Sep 2024  ·  doi:10.1016/j.heliyon.2024.e36728
Deep learning for the harmonization of structural MRI scans: a survey.
Soolmaz Abbasi, Haoyu Lan, Jeiran Choupan, Nasim Sheikh-Bahaei, Gaurav Pandey, Bino Varghese
Biomedical engineering online  ·  31 Aug 2024  ·  pubmed:39217355
Prediction of future dementia among patients with mild cognitive impairment (MCI) by integrating multimodal clinical data.
Andrew Cirincione, Kirsten Lynch, Jamie Bennett, Jeiran Choupan, Bino Varghese, Nasim Sheikh-Bahaei, Gaurav Pandey
Heliyon  ·  22 Aug 2024  ·  pubmed:39281465
Technical and clinical considerations of a physical liver phantom for CT radiomics analysis
Bino Abel Varghese, Steven Yong Cen, Kristin Jensen, Joshua Levy, Hilde Kjernlie Andersen, Anselm Schulz, Xiaomeng Lei, Vinay Anant Duddalwar, David John Goodenough
Journal of Applied Clinical Medical Physics  ·  22 Feb 2024  ·  doi:10.1002/acm2.14309
Technical and clinical considerations of a physical liver phantom for CT radiomics analysis.
Bino Abel Varghese, Steven Yong Cen, Kristin Jensen, Joshua Levy, Hilde Kjernlie Andersen, Anselm Schulz, Xiaomeng Lei, Vinay Anant Duddalwar, David John Goodenough
Journal of applied clinical medical physics  ·  22 Feb 2024  ·  pubmed:38386922
Empowering breast cancer diagnosis and radiology practice: advances in artificial intelligence for contrast-enhanced mammography.
Ketki K Kinkar, Brandon K K Fields, Mary W Yamashita, Bino A Varghese
Frontiers in radiology  ·  05 Jan 2024  ·  pubmed:38249158
Conditional generative learning for medical image imputation
Ragheb Raad, Deep Ray, Bino Varghese, Darryl Hwang, Inderbir Gill, Vinay Duddalwar, Assad A. Oberai
Scientific Reports  ·  02 Jan 2024  ·  doi:10.1038/s41598-023-50566-7
Conditional generative learning for medical image imputation.
Ragheb Raad, Deep Ray, Bino Varghese, Darryl Hwang, Inderbir Gill, Vinay Duddalwar, Assad A Oberai
Scientific reports  ·  02 Jan 2024  ·  pubmed:38167932

2023

Investigating the role of imaging factors in the variability of CT‐based texture analysis metrics
Bino Abel Varghese, Steven Yong Cen, Kristin Jensen, Joshua Levy, Hilde Kjernlie Andersen, Anselm Schulz, Xiaomeng Lei, Vinay Anant Duddalwar, David John Goodenough
Journal of Applied Clinical Medical Physics  ·  14 Nov 2023  ·  doi:10.1002/acm2.14192
Investigating the role of imaging factors in the variability of CT-based texture analysis metrics.
Bino Abel Varghese, Steven Yong Cen, Kristin Jensen, Joshua Levy, Hilde Kjernlie Andersen, Anselm Schulz, Xiaomeng Lei, Vinay Anant Duddalwar, David John Goodenough
Journal of applied clinical medical physics  ·  14 Nov 2023  ·  pubmed:37962032
A Narrative Review of the Use of Artificial Intelligence in Breast, Lung, and Prostate Cancer.
Kishan Patel, Sherry Huang, Arnav Rashid, Bino Varghese, Ali Gholamrezanezhad
Life (Basel, Switzerland)  ·  04 Oct 2023  ·  pubmed:37895393
A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength.
Mark S Shiroishi, Dane Weinert, Steven Y Cen, Bino Varghese, Timothy Dondlinger, …, Leland S Hu, C Chad Quarles, Jerrold L Boxerman, Ona Wu, Kathleen M Schmainda
Frontiers in oncology  ·  20 Sep 2023  ·  pubmed:37799462
Radiomics Correlation to CD68+ Tumor-Associated Macrophages in Clear Cell Renal Cell Carcinoma.
Alexander Shieh, Steven Y Cen, Bino A Varghese, Darryl Hwang, Xiaomeng Lei, …, Manju Aron, Anishka Dsouza, Inderbir S Gill, William Wallace, Vinay Duddalwar
Oncology  ·  12 Sep 2023  ·  pubmed:37699367
Spatial assessments in texture analysis: what the radiologist needs to know.
Bino A Varghese, Brandon K K Fields, Darryl H Hwang, Vinay A Duddalwar, George R Matcuk, Steven Y Cen
Frontiers in radiology  ·  24 Aug 2023  ·  pubmed:37693924
Sarcopenia and body fat change as risk factors for radiologic incisional hernia following robotic nephrectomy.
Simin Hajian, Alireza Ghoreifi, Steven Yong Cen, Bino Varghese, Xiaomeng Lei, …, Khoa Tran, Tapas Tejura, Gilbert Whang, Hooman Djaladat, Vinay Duddalwar
Skeletal radiology  ·  30 May 2023  ·  pubmed:37249596
Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study.
Derek H Liu, Komal A Dani, Sharath S Reddy, Xiaomeng Lei, Natalie L Demirjian, …, Ulka Vaishampayan, Haris Zahoor, Steven Y Cen, Inderbir S Gill, Vinay A Duddalwar
Oncology  ·  20 Apr 2023  ·  pubmed:37080171
Predicting Soft Tissue Sarcoma Response to Neoadjuvant Chemotherapy Using an MRI-Based Delta-Radiomics Approach.
Brandon K K Fields, Natalie L Demirjian, Steven Y Cen, Bino A Varghese, Darryl H Hwang, Xiaomeng Lei, Bhushan Desai, Vinay Duddalwar, George R Matcuk
Molecular imaging and biology  ·  25 Jan 2023  ·  pubmed:36695966

2022

Feasibility of using CT radiomic signatures for predicting CD8-T cell infiltration and PD-L1 expression in renal cell carcinoma.
Bino Varghese, Steven Cen, Haris Zahoor, Imran Siddiqui, Manju Aron, …, David Quinn, Mihir Desai, Ulka Vaishampayan, Inderbir Gill, Vinay Duddalwar
European journal of radiology open  ·  02 Sep 2022  ·  pubmed:36090617
Radiomics quality score in renal masses: a systematic assessment on current literature.
Afshin Azadikhah, Bino Abel Varghese, Xiaomeng Lei, Chloe Martin-King, Steven Yong Cen, Vinay Anant Duddalwar
The British journal of radiology  ·  15 Jun 2022  ·  pubmed:35671097
An Extra Set of Intelligent Eyes: Application of Artificial Intelligence in Imaging of Abdominopelvic Pathologies in Emergency Radiology.
Jeffrey Liu, Bino Varghese, Farzaneh Taravat, Liesl S Eibschutz, Ali Gholamrezanezhad
Diagnostics (Basel, Switzerland)  ·  30 May 2022  ·  pubmed:35741161
Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis.
Gareth Morrison, Jonathan Buckley, Dejerianne Ostrow, Bino Varghese, Steven Y Cen, …, Jeffrey Smith, David Quinn, Vinay Duddalwar, Timothy Triche, Amir Goldkorn
International journal of molecular sciences  ·  25 Feb 2022  ·  pubmed:35269713
Characterizing breast masses using an integrative framework of machine learning and CEUS-based radiomics
Bino A. Varghese, Sandy Lee, Steven Cen, Amir Talebi, Passant Mohd, Daniel Stahl, Melissa Perkins, Bhushan Desai, Vinay A. Duddalwar, Linda H. Larsen
Journal of Ultrasound  ·  17 Jan 2022  ·  doi:10.1007/s40477-021-00651-2
Characterizing breast masses using an integrative framework of machine learning and CEUS-based radiomics.
Bino A Varghese, Sandy Lee, Steven Cen, Amir Talebi, Passant Mohd, Daniel Stahl, Melissa Perkins, Bhushan Desai, Vinay A Duddalwar, Linda H Larsen
Journal of ultrasound  ·  17 Jan 2022  ·  pubmed:35040103

2021

CT-based radiomics stratification of tumor grade and TNM stage of clear cell renal cell carcinoma.
Natalie L Demirjian, Bino A Varghese, Steven Y Cen, Darryl H Hwang, Manju Aron, …, Derek H Liu, Mihir Desai, Suhn K Rhie, Inderbir S Gill, Vinay Duddalwar
European radiology  ·  10 Nov 2021  ·  pubmed:34757449
Benchmarking Various Radiomic Toolkit Features While Applying the Image Biomarker Standardization Initiative toward Clinical Translation of Radiomic Analysis.
Mingxi Lei, Bino Varghese, Darryl Hwang, Steven Cen, Xiaomeng Lei, Bhushan Desai, Afshin Azadikhah, Assad Oberai, Vinay Duddalwar
Journal of digital imaging  ·  20 Sep 2021  ·  pubmed:34545475
A Radiomic-based Machine Learning Algorithm to Reliably Differentiate Benign Renal Masses from Renal Cell Carcinoma.
Nima Nassiri, Marissa Maas, Giovanni Cacciamani, Bino Varghese, Darryl Hwang, …, Mihir Desai, Assad A Oberai, Steven Y Cen, Inderbir S Gill, Vinay A Duddalwar
European urology focus  ·  16 Sep 2021  ·  pubmed:34538748
Predicting clinical outcomes in COVID-19 using radiomics on chest radiographs.
Bino Abel Varghese, Heeseop Shin, Bhushan Desai, Ali Gholamrezanezhad, Xiaomeng Lei, Melissa Perkins, Assad Oberai, Neha Nanda, Steven Cen, Vinay Duddalwar
The British journal of radiology  ·  14 Sep 2021  ·  pubmed:34520246
Whole-tumor 3D volumetric MRI-based radiomics approach for distinguishing between benign and malignant soft tissue tumors.
Brandon K K Fields, Natalie L Demirjian, Darryl H Hwang, Bino A Varghese, Steven Y Cen, Xiaomeng Lei, Bhushan Desai, Vinay Duddalwar, George R Matcuk
European radiology  ·  23 Apr 2021  ·  pubmed:33893534
Identification of robust and reproducible CT‐texture metrics using a customized 3D‐printed texture phantom
Bino A. Varghese, Darryl Hwang, Steven Y. Cen, Xiaomeng Lei, Joshua Levy, Bhushan Desai, David J. Goodenough, Vinay A. Duddalwar
Journal of Applied Clinical Medical Physics  ·  12 Jan 2021  ·  doi:10.1002/acm2.13162
Identification of robust and reproducible CT-texture metrics using a customized 3D-printed texture phantom.
Bino A Varghese, Darryl Hwang, Steven Y Cen, Xiaomeng Lei, Joshua Levy, Bhushan Desai, David J Goodenough, Vinay A Duddalwar
Journal of applied clinical medical physics  ·  12 Jan 2021  ·  pubmed:33434374

2020

Open collaborative writing with Manubot
Daniel S. Himmelstein, Vincent Rubinetti, David R. Slochower, Dongbo Hu, Venkat S. Malladi, Casey S. Greene, Anthony Gitter
PLOS Computational Biology  ·  04 Dec 2020  ·  doi:10.1371/journal.pcbi.1007128
Shape and texture-based radiomics signature on CT effectively discriminates benign from malignant renal masses.
Felix Y Yap, Bino A Varghese, Steven Y Cen, Darryl H Hwang, Xiaomeng Lei, …, Mihir M Desai, Monish Aron, Assad A Oberai, Inderbir S Gill, Vinay A Duddalwar
European radiology  ·  15 Aug 2020  ·  pubmed:32803417
Deep learning based classification of solid lipid-poor contrast enhancing renal masses using contrast enhanced CT.
Assad Oberai, Bino Varghese, Steven Cen, Tomas Angelini, Darryl Hwang, Inderbir Gill, Manju Aron, Christopher Lau, Vinay Duddalwar
The British journal of radiology  ·  11 May 2020  ·  pubmed:32356484
Quantitative magnetic resonance imaging (q-MRI) for the assessment of soft-tissue sarcoma treatment response: a narrative case review of technique development.
Brandon K K Fields, Darryl Hwang, Steven Cen, Bhushan Desai, Mittul Gulati, James Hu, Vinay Duddalwar, Bino Varghese, George R Matcuk
Clinical imaging  ·  28 Feb 2020  ·  pubmed:32163847
Constructing knowledge graphs and their biomedical applications
David N. Nicholson, Casey S. Greene
Computational and Structural Biotechnology Journal  ·  01 Jan 2020  ·  doi:10.1016/j.csbj.2020.05.017

2019

Myocardial Radiomics in Cardiac MRI.
Cameron Hassani, Farhood Saremi, Bino A Varghese, Vinay Duddalwar
AJR. American journal of roentgenology  ·  04 Dec 2019  ·  pubmed:31799865
Reliability of CT-based texture features: Phantom study.
Bino A Varghese, Darryl Hwang, Steven Y Cen, Joshua Levy, Derek Liu, Christopher Lau, Marielena Rivas, Bhushan Desai, David J Goodenough, Vinay A Duddalwar
Journal of applied clinical medical physics  ·  20 Jun 2019  ·  pubmed:31222919
Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images
Bino Varghese, Frank Chen, Darryl Hwang, Suzanne L Palmer, Andre Luis De Castro Abreu, …, Monish Aron, Manju Aron, Inderbir Gill, Vinay Duddalwar, Gaurav Pandey
Scientific Reports  ·  07 Feb 2019  ·  doi:10.1038/s41598-018-38381-x
Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images.
Bino Varghese, Frank Chen, Darryl Hwang, Suzanne L Palmer, Andre Luis De Castro Abreu, …, Monish Aron, Manju Aron, Inderbir Gill, Vinay Duddalwar, Gaurav Pandey
Scientific reports  ·  07 Feb 2019  ·  pubmed:30733585
Texture Analysis of Imaging: What Radiologists Need to Know.
Bino A Varghese, Steven Y Cen, Darryl H Hwang, Vinay A Duddalwar
AJR. American journal of roentgenology  ·  15 Jan 2019  ·  pubmed:30645163
Radiomics in Pulmonary Lesion Imaging.
Cameron Hassani, Bino A Varghese, Jorge Nieva, Vinay Duddalwar
AJR. American journal of roentgenology  ·  08 Jan 2019  ·  pubmed:30620678
Computed tomography-based texture analysis of bladder cancer: differentiating urothelial carcinoma from micropapillary carcinoma.
Ting-Wei Fan, Harshawn Malhi, Bino Varghese, Steve Cen, Darryl Hwang, Manju Aron, Nieroshan Rajarubendra, Mihir Desai, Vinay Duddalwar
Abdominal radiology (New York)  ·  01 Jan 2019  ·  pubmed:30022220

2018

A Decision-Support Tool for Renal Mass Classification.
Gautam Kunapuli, Bino A Varghese, Priya Ganapathy, Bhushan Desai, Steven Cen, Manju Aron, Inderbir Gill, Vinay Duddalwar
Journal of digital imaging  ·  01 Dec 2018  ·  pubmed:29980960
Differentiation of Predominantly Solid Enhancing Lipid-Poor Renal Cell Masses by Use of Contrast-Enhanced CT: Evaluating the Role of Texture in Tumor Subtyping.
Bino A Varghese, Frank Chen, Darryl H Hwang, Steven Y Cen, Bhushan Desai, Inderbir S Gill, Vinay A Duddalwar
AJR. American journal of roentgenology  ·  21 Sep 2018  ·  pubmed:30240299
Incidental Detection of Meningioma by 18F-FMAU PET/CT in a Patient With Suspected Prostate Cancer.
Bino Varghese, Erik Velez, Bhushan Desai, Hossein Jadvar
Clinical nuclear medicine  ·  01 Jul 2018  ·  pubmed:29742600
Differentiating solid, non-macroscopic fat containing, enhancing renal masses using fast Fourier transform analysis of multiphase CT.
Bino A Varghese, Frank Chen, Darryl H Hwang, Steven Y Cen, Inderbir S Gill, Vinay A Duddalwar
The British journal of radiology  ·  21 Jun 2018  ·  pubmed:29888982
Avian tail ontogeny, pygostyle formation, and interpretation of juvenile Mesozoic specimens.
Dana J Rashid, Kevin Surya, Luis M Chiappe, Nathan Carroll, Kimball L Garrett, Bino Varghese, Alida Bailleul, Jingmai K O’Connor, Susan C Chapman, John R Horner
Scientific reports  ·  13 Jun 2018  ·  pubmed:29899503
Sci-Hub provides access to nearly all scholarly literature
Daniel S Himmelstein, Ariel Rodriguez Romero, Jacob G Levernier, Thomas Anthony Munro, Stephen Reid McLaughlin, Bastian Greshake Tzovaras, Casey S Greene
eLife  ·  01 Mar 2018  ·  doi:10.7554/eLife.32822
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
Beiyun Zhou, Per Flodby, Jiao Luo, Dan R Castillo, Yixin Liu, …, Parviz Minoo, Kunliang Guan, Barry R Stripp, Edward D Crandall, Zea Borok
The Journal of clinical investigation  ·  05 Feb 2018  ·  pubmed:29400695
Quantitative Contour Analysis as an Image-based Discriminator Between Benign and Malignant Renal Tumors.
Felix Y Yap, Darryl H Hwang, Steven Y Cen, Bino A Varghese, Bhushan Desai, …, Manju Aron, Gangning Liang, Monish Aron, Inderbir S Gill, Vinay A Duddalwar
Urology  ·  02 Jan 2018  ·  pubmed:29305199

2017

Liver-Directed Human Amniotic Epithelial Cell Transplantation Improves Systemic Disease Phenotype in Hurler Syndrome Mouse Model.
Natalie S Rodriguez, Lisa Yanuaria, Kevin Murphy R Parducho, Irving M Garcia, Bino A Varghese, Brendan H Grubbs, Toshio Miki
Stem cells translational medicine  ·  06 Jun 2017  ·  pubmed:28585336
Voxel-based whole-lesion enhancement parameters: a study of its clinical value in differentiating clear cell renal cell carcinoma from renal oncocytoma.
Frank Chen, Mittul Gulati, Darryl Hwang, Steven Cen, Felix Yap, …, Bino Varghese, Mihir Desai, Manju Aron, Inderbir Gill, Vinay Duddalwar
Abdominal radiology (New York)  ·  01 Feb 2017  ·  pubmed:27595574

2015

Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers.
Shanshan He, Zhen Zhao, Yongfei Yang, Douglas O’Connell, Xiaowei Zhang, …, Yong Zhang, Guo-Min Li, Sue Ellen Martin, Keigo Machida, Chengyu Liang
Nature communications  ·  03 Aug 2015  ·  pubmed:26234763

2014

A microfluidic technique to probe cell deformability.
David J Hoelzle, Bino A Varghese, Clara K Chan, Amy C Rowat
Journal of visualized experiments : JoVE  ·  03 Sep 2014  ·  pubmed:25226269

2011

Computed-tomography-based finite-element models of long bones can accurately capture strain response to bending and torsion.
Bino Varghese, David Short, Ravi Penmetsa, Tarun Goswami, Thomas Hangartner
Journal of biomechanics  ·  01 Feb 2011  ·  pubmed:21288523