The AIMR Lab Keck School of Medicine

Projects

Our lab harnesses advanced deep learning and image processing techniques to push the boundaries of medical diagnostics. Through multidisciplinary projects, we develop cutting-edge solutions that enhance image quality, automate feature detection, and improve early disease diagnosis, paving the way for smarter, more accurate clinical decision-making.

DL-based Automated Lesion Segmentation
DL-based Automated Lesion Segmentation

Pre-trained U-Net models with EfficientNetB0, VGG16, and DenseNet121 backbones were fine-tuned on a large dataset of CEM images with separate validation and independent testing sets, and evaluated using IoU and Dice scores over multiple training epochs.

Radiomics-based Automated Hotspot Segmentation
Radiomics-based Automated Hotspot Segmentation

A novel TVHC approach leveraging radiomic skewness masks, morphological operations, and chest wall segmentation on annotated mammograms to detect hotspots, with classification performed using multiple deep learning models and AUROC-based performance comparisons.

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MRI (Super Resolution)
MRI (Super Resolution)

A novel deep learning framework leveraging multi-scale CNN architectures and adversarial training to reconstruct high-resolution MRI images from low-resolution inputs, with enhanced feature fusion and perceptual loss optimization, and performance validated using quantitative metrics.

CEUS Motion Compensation
CEUS Motion Compensation

A novel deep learning framework leveraging spatio-temporal modeling and optical flow estimation to correct for motion artifacts in contrast-enhanced ultrasound imaging, enhancing image clarity and diagnostic reliability.

Early AD Detection
Early AD Detection

A novel multimodal deep learning framework integrating MRI-based neuroimaging with retinal biomarker analysis to facilitate early Alzheimer’s diagnosis through advanced feature extraction and fusion techniques.